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As a key methyltransferase of m6A, METTL3 can inhibit the activation of pTHP-1 macrophages by preventing the generation of IL-6 and TNF-, and attenuate inflammatory response induced by LPS via the NF-B signaling pathway (178)

Because of this reading, I believe DACs could open new competitive space, keen to understand from industry leaders, what level of awareness and interest is your organization seeing around DAC and antibody-conjugated degrader platforms

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