gst glutathione transferase transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases Overexpression of Glutathione S-Transferases in

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This energy exhaustion will further lead to the production of reactive oxygen species (ROS), apoptosis, and abnormal calcium homeostasis, which will promote epilepsy, thus forming a vicious circle (5)

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We examined 65 patients with septic shock and found that the 29 deceased individuals exhibited significantly higher plasma R-GSSG activity, indicating an excessive inflammatory response