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Interruption of therapy as a result of GI tolerability issues was reported in 212% of patients in oral semaglutide groups [1, 9, 12,13,14, 16,17,18]

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Besides, consistently higher paracetamol regimen may minimize all problems related to possible variations from animal to animal and from time to time in a given animal and invariably link paracetamol action with seizures, severely damaged brain tissue, hepatomegaly, fatty liver and necrosis, breakdown of liver function with profoundly increased ammonia, AST and ALT levels