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Each has been studied individually in animal research for: Researchers pair them because these mechanisms are complementary rather than overlapping

The major esterase enzymes responsible for hydrolyzing aspirin include carboxypeptidase in the liver, pseudocholinesterase in the plasma, and acetylhydrolase I, an intracellular enzyme found in erythrocytes (Ornelas et al, 2017)

Fluoride 39(2):95100 Waugh DT (2019) Fluoride exposure induces inhibition of sodium/iodide symporter (NIS) contributing to impaired iodine absorption and iodine deficiency: molecular mechanisms of inhibition and implications for public health

If you have to pick one, the decision usually comes down to whether your primary issue is soft-tissue injury (either works) or gut inflammation (BPC-157)