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The short answer is that semaglutide and other GLP-1 agonists do not appear as detectable substances on standard laboratory panels, since these medications work by activating your body's own receptors rather than adding a foreign marker to your bloodstream

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The peptide consists of eight amino acids (octapeptide) with the sequence Acetyl-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH

Tirzepatide sold as Mounjaro and Zepbound does the same and adds a second gut hormone, GIP (glucose-dependent insulinotropic polypeptide), which is why it's called a dual agonist