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Clinical Benefits & Effects

The program established a favorable safety profile but the Phase IIb endpoint did not differentiate sufficiently from placebo to support continued development for obesity

Results build gradually over months: better sleep first, then body composition, then skin improvements

A diet low in MACs may also impair the ability of the intestinal microbiota to recover following antibiotic exposure and ultimately increase the likelihood of prolonged damage to the intestinal barrier (Ng et al

Research has also examined its role in enteric neuron survival, enteric glial cell activity, gut motility modulation, and gut-brain axis signaling in experimental settings