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Melanin is the pigment responsible for skin color, and its overproduction leads to darker skin tones and hyperpigmentation

Furthermore, tPA intervention increased brain matrix metalloproteinase (MMP-9) (Yang et al., 2016), as well as phosphorylation of connexin43, a gap junction protein contributing to blood brain barrier permeability and hemorrhagic transformation (Tang and Han, 2013)

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It's a compound with a well-characterized mechanism, positive animal data, and a cluster of smaller human studies pointing in the right direction

Studied in research involving synergistic tissue repair signaling, inflammatory modulation, and regenerative biology