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Patients should contact their GP urgently if neurological symptoms worsen, new symptoms develop, or signs of liver decompensation appear, as this may indicate inadequate treatment response or disease progression requiring specialist review

NAC, N-acetylcysteine

Mechanism of Action: Glutathione is a major endogenous antioxidant produced by the cells, participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintains exogenous antioxidants such as vitamins C and E in their active form

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In phase 2 trials, cagrilintide alone produced dose-dependent reductions in body weight, with participants on the highest dose (4.5 mg weekly) losing roughly 10-15% of body weight over 26 weeks