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Defects in CI biogenesis are the most common cause of mitochondrial disorders and are linked to age-related diseases, including neurodegeneration 34

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In addition, centrilobular necrosis, cellular hypertrophy and vacuolization were observed (Figures 3C, D)

They are prescribed to individuals who struggle with obesity or are overweight with at least one weight-related condition, such as hypertension, high cholesterol, or Type 2 diabetes

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