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As acyl-carnitine derivatives, fatty acids pass through mitochondrial membranes and enter pathways for oxidation, acylation, chain shortening, or chain elongation-desaturation (Cha 2008)

Microdosing involves taking small, fractional, or sub-therapeutic doses that are used off-label to get potential benefits from the medication with minimal side effects

secondary endpoints included Psychometric HE-score (PHES), Clinical Global Assessment of HE (CGA-HE), and frequency of occurrences of overt HE and hospitalization

"People living with obesity have long been denied access to the essential treatment and care needed to manage this serious chronic disease," said James Zervos, chief operating officer, Obesity Action Coalition