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Currently, key processes leading to neurodegeneration are considered to be oxidative stress, disruption of transition metal homeostasis, and inflammation of the nervous system

Magnesium deficiency, present in an estimated 60 percent of Indians due to soil depletion and dietary patterns, impairs the enzymatic function of ATP synthesis, DNA repair, and protein production that all longevity mechanisms depend upon

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Later occurrence of gastrointestinal symptoms could be due to lactic acidosis or other serious disease

Keywords: Tourette syndrome, GABA, gut microbiota, striatum metabolism Introduction Tourette syndrome (TS) is a common neurobehavioral and neuropsychiatric disorder typically occurring in childhood, 1 with an estimated prevalence of approximately 1% in children and adolescents of the world