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In the SOUL trial (Semaglutide cardiOvascular oUtcomes trial) just published in May 2025, 9650 participants 50 years of age or older who had T2D with a HbA1c of 6.5 to 10.0%, and had known atherosclerotic cardiovascular disease, chronic kidney disease, or both to receive either once-daily oral semaglutide (maximal dose, 14 mg) or placebo, in addition to standard care (5)

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