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When someone carries excess weight AND has an autoimmune condition, they face a compounding problem: obesity-driven inflammation amplifies autoimmune-driven inflammation, creating a feedback loop that standard immunosuppressive therapies struggle to fully address

Recently, a surfactant conjugated co-agonist peptide 17 was shown to have a half-life of 52 hours in vivo and at a higher dose led to 40% body weight loss in obese rats over 27 days (79)

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Diindolylmethane (DIM) spontaneously forms from indole-3-carbinol (I3C) during cell culture experiments