Ahmed, M
Markers of a poor diet, such as high intake of saturated fats and sugar, have been linked to lower male fertility, whereas markers of healthy eating, such as balanced intake of omega-3 and omega-6 fatty acids, high consumption of whole grains, and a diversity of fruits and vegetables providing ample amounts of essential vitamins and minerals, have been correlated with better sperm parameters
Its working mechanism is allosteric facilitation of HGF/c-Met signaling: Dihexa binds HGF with high affinity (reported K d ~65 pM in the original work) and is proposed to potentiate HGF dimerization and c-Met phosphorylation at subthreshold endogenous HGF concentrations
Uso de laboratorio nicamente (RUO)
ORCID: Affiliation: 6 Instituto de Farmacologia e Neurocincias, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal 7 Centro Cardiovascular da Universidade de Lisboa, CCUL (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal These authors contributed equally to this work