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The molecular link between mitochondrial oxidative stress/DNA damage and ferroptosis in LN (223) is also poorly defined: it is unknown whether mitochondrial dysfunction directly triggers iron overload/lipid peroxidation or indirectly by suppressing antioxidant networks (e.g., Nrf2/GPX4)

Li H, Toh PZ, Tan JY, Zin MT, Lee CY, Li B

Taurine levels in the human brain are typically reported to be approximately 12 mM, while in the mouse brain, they are approximately 510 times greater (21)

Liraglutide, in particular, has a half-life of only around 13 hours and requires a daily injection

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