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In addition, fasting blood glucose and hemoglobin A1c levels improved when liraglutide was administered to adults without diabetes

Neurosci Lett 328:5559 Song TY, Yang NC, Chen CL, Thi TLV (2017) Protective Effects and Possible Mechanisms of Ergothioneine and Hispidin against Methylglyoxal-Induced Injuries in Rat Pheochromocytoma Cells

That single D-residue is what makes the peptide resistant to peptidases and gives it its remarkable potency at the mu-opioid receptor