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FDA requires PBE analysis on the ovality ratio and spray area for ANDA submissions

RhoA/rho kinase pathway activation in age-associated endothelial cell dysfunction and thrombosis

Perhaps relevant to the previous connection are the findings suggesting that nitric oxide synthase (NOS, an enzyme widely expressed throughout the brain and which is responsible for NO production in the central nervous system) inhibitors protect against phencyclidine (PCP) induced schizophrenia-mimicing phenotypes such as PPI deficits and cognitive inflexibility in animals (Johansson et al

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Fat-soluble toxins are converted into intermediate metabolites that are more chemically reactive and biologically accessible for downstream processing