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If you are switching between the two (covered in detail in our conversion guide ), you do not need to change your injection site habits

Additionally, despite the rise in E 2 , most patients did not experience symptoms/signs of hyperestrogenism

Others may experience intensified nausea, digestive symptoms, dehydration, or blood sugar fluctuations, especially during dose increases or when drinking on an empty stomach

When taken as sublingual drops, the medication is absorbed under the tongue, signaling the body to feel fuller, reduce cravings, and improve how food is used for energy

Summary of NICE guidance for GLP-1 receptor agonists and tirzepatide in adults (NG28)