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General subcutaneous injection sites include the abdomen, outer thigh, and back/side of the upper arm when a clinician has prescribed a subcutaneous medicine

Although there is evidence that DPP-4 inhibitors confer cardiovascular safety and renoprotection, the potential risks of hospitalization for heart failure and acute pancreatitis are disadvantages to their use as add-on therapy

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From a scientific perspective, the next critical step would be rigorous, independent, international clinical trials with proper controls, blinding, and standardized outcome measures