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Bioorg Med Chem (2013) 21(22):706473
7 Still, Le, who is also a general surgery registrar at Royal Melbourne Hospital, says, I think it is too early to say this is a robust, durable, and generalizable effect given the high heterogeneity of underlying studies. He notes a need for more rigorous randomized controlled trials with longer follow-up times to better characterize the impact of these medications on weight and OSA together, as well as gain a better understanding of effect size, optimal doses, side effects, interactions with other medications, and impacts on other comorbidities
4.4 Potential effects of tirzepatide on upper airway function In addition to metabolic and inflammatory modulation, emerging evidence suggests that incretin-based therapies may influence upper airway neuromuscular control
Current clinical data shows GLP-1 medications reduce body weight by 15-22% in structured programs, though individual responses vary significantly based on genetic and metabolic factors
Ultimately, the science behind GHK-Cu proves its not just another passing trend
