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It is gentle enough to tolerate with proper introduction, strong enough to produce clinical results, and widely available without a prescription

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While bronchoscopy is not routinely recommended [87, 88], flexible bronchoscopes are increasingly used on ICU for airway clearance and sampling of respiratory secretions, where less invasive methods are insufficient [88]

Idiopathic rapid eye movement sleep behavior disorder (iRBD) represents a well-known precursor phase of PD, in which pathology is thought to have reached the lower brainstem [44]