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Use caution in patients with a history of anaphylaxis or angioedema to other GLP-1 receptor agonists because it is unknown whether such patients will be predisposed to serious reactions with semaglutide

A recurring theme across review platforms is the difficulty of reaching anyone at Empower

Reconstitution in 0.1% acetic acid (10 mM) is common practice, as the peptide tends to aggregate in neutral aqueous solutions without an acidifying agent

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Ultra-fast responders, representing perhaps 20-30% of users, notice improvement within the first 1-3 days