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2.1.5 Synergism with metabolic syndrome Gout is closely associated with metabolic syndrome components, including obesity, insulin resistance, and hypertension (Pascart and Liote, 2019)

However, it is important to strike that although these data underscore the significance of GSH depletion for a short period of time (up to 24 hours), it is conceivable that depletion of GSH per se for serveral days may result in a different outcome