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The consensus also points out that the median Hcy for adults in China is in the range of 1314 umol/L, exceeding the diagnostic standard by more than 30% (1)

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Caution is recommended in individuals with seizure disorders, as increased frequency or severity of seizures has been reported during therapy

Genetic factors associated with serum UA can be used as an explicit proxy for serum UA concentration, permitting the assessment of its potential causal relationship with PD, a technique referred to as Mendelian randomisation (MR)