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Even a recent 2026 review concludes the same thing that GHK-Cu appears safe but the evidence is largely preclinical and comprehensive human RCTs are lacking (Wojcieszuk et al., 2026)

It inhibits the reuptake of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), leading to prolonged monoaminergic neurotransmission

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