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Providers should emphasize the importance of adequate hydration and provide clear instructions for managing nausea, which peaks during the first 8-12 weeks of therapy

Most patients begin to observe visible changes after a few weeks of continued use, as the medication helps reduce calorie intake and improve metabolic control over time

GLUT4 regulation: MOTS-c increases the translocation of GLUT4 glucose transporters to the muscle cell membrane, improving how muscle takes up glucose from the bloodstream

1,5 If you wish to restart Wegovy after pregnancy, the recommended sequence is to wean first, then resume the medication