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Nanoparticles that synergize with iron metabolism (such as chitosan-arabinogalactan/iron complexes CSAA/Fe@PPI) significantly enhance the ferroptosis effect by delivering exogenous Fe 3+ and inducing ferroptin autophagy, which increases the level of the LIP in cells and the lipid peroxidation marker 4-HNE (239)
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Oral supplements often have limited and variable absorption rates through the digestive system, meaning much of the nutrient content may not reach your cells
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