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In tumor cells, sodium butyrate (NaB) promotes ferroptosis by enhancing ROS production and depleting GSH via the free fatty acid receptor 2/cyclic adenosine monophosphate/ protein kinase A axis (Wang et al., 2023)

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Studies tracking weight loss outcomes showed that sermorelin users lost more fat while preserving muscle compared to control groups

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Since mTOR is located downstream of AMPK and mTOR has been well reported to regulate muscle growth and metabolism 42,43 as well as the eIF4EBP3L as a gatekeeper of mTOR in muscle growth 44 , we next examined the effect of mTOR pathway by measuring the levels of mTOR and eif4ebp3l in the LMNA mutant transgenic fish with or without drug treatment