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Gradual weight loss typically starts within the first few weeks, but significant weight loss generally occurs over 12 to 16 weeks as your body adjusts

Never double up on doses

These drugs ability to help patients lose anywhere from 15% to 20% of body weight has made them one of the most powerful nonsurgical obesity treatments ever seen

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In terms of tolerability, tirzepatide generally causes fewer gastrointestinal side effects, making it a better option for those sensitive to nausea, while Semaglutide GLP-1 may cause mild to moderate gastrointestinal issues like nausea and diarrhea, which usually subside over time