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Swelling may be more widespread, and the overall physical demand on the body is greater

For the head and neck refer to the chapter Melanoma: lentigo maligna melanoma (including lentigo maligna) Pattern comparison It is important to examine all of a patient's moles - a melanoma / other skin cancer is likely to look different to the others Dermal naevi - globular / cobblestone Morphology Thickened and often protrude from the skin surface May become dome-shape or papillomatous and wobbly to palpate Colour - often brown

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An overview of Helicobacter pylori VacA toxin biology