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Most relevant peptides: Thymosin alpha-1 for restoring T cell regulation and reducing autoantibody production KPV for systemic NF-kB inhibition and cytokine reduction An important lupus-specific peptide in clinical development is P140/Lupuzor, a 21-amino-acid phosphopeptide that has completed Phase IIb clinical trials and entered Phase III trials for SLE

10.1016/j.fertnstert.2014.05.039 115