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Metabolic checkpoint of ferroptosis resistance

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Endothelial cell dysfunction is an initial step in atherosclerotic lesion formation and is more likely to occur at arterial curves and branches that are subjected to low shear stress and disturbed blood flow (atherosclerosis prone areas) (7,8)

As their names suggest these syndromes are marked by increased oxidative stress and damaged redox states

CEBPbeta regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth