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When to seek help red flags: Contact your GP or trial clinician promptly if you experience persistent or worsening nausea and vomiting, are unable to keep fluids down for more than 24 hours, or notice significant unintentional weight loss or difficulty maintaining adequate nutrition

The dose-response lines were fitted using least-squares linear regression, and their 95% confidence intervals were calculated according to the previously described method

( j-k ) Representative images and related quantification of axillary spleens and lymph nodes

Minori Koga for experimental support and discussions

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