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42,43 For example, by inhibiting histone deacetylase (HDAC) activity, SCFAs promote mitochondrial oxidative phosphorylation as well as glycolysis, which are essential for robust plasma B cell generation

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In the context of limited glutamine, various cell components in the TME compete for glutamine, and tumor cells can increase their uptake of glutamine due to their unique metabolic mode, thus providing certain competitive advantages