Consistent with an induction of oxidative stress condition, metformin increased mRNA levels of the master redox transcription factor Nrf-2 (nuclear factor erythroid-derived 2-like), as well as transsulfuration enzymes cystathionine beta-synthase and cystathionase and GSH synthesis enzymes -glutamylcysteine synthetase and glutathione synthetase
For example [49], reported elevated levels of nitric oxide (NO) and malondialdehyde (MDA), alongside decreased superoxide dismutase (SOD) activity and reduced glutathione (GSH) levels in the bronchoalveolar lavage fluids and lung tissues of Hg- exposed rats
At the same concentration (50 M), T1 causes a higher degree of transparency (reducing around 41.4% of pigmentation production) than those seen in -arbutin and kojic acid, indicating that the de-pigmenting effect of T1 is far more efficient than those of the high dose-dependent -arbutin and kojic acid (Fig
Foods Containing Glutathione Source: Jones et al., Nutr Cancer, 1992
Got tired of maintaining the hairs under the pits on a weekly basis