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Overall, these findings in HIV patients provide proof-of-concept that dietary supplementation of GlyNAC improves multiple hallmarks of aging and that glutathione deficiency and oxidative stress could contribute to them

For example, the ongoing ViTAL-SCAN19 Trial (registered under ClinicalTrials.gov NCT06967428) is evaluating a metabolic modulator protocol for Long COVID cohorts that includes a massive daily dose of 14 grams of L-Glutamine, combined with N-acetylcysteine (NAC) and other amino acids

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