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In multiple paradigms, animals given GLP-1 agonists reduced their substance intake by 40-60%, even when the substances were freely available

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However, the enthusiasm around Ozempic has started to wane as people have realized that the drug comes with numerous side effects

Rabiee A, Galiatsatos P, Salas-Carrillo R et al (2011) Pancreatic polypeptide administration enhances insulin sensitivity and reduces the insulin requirement of patients on insulin pump therapy

This is why manufacturers and healthcare providers recommend discarding any pen that has been frozen, exposed to excessive heat or stored outside guidelines for an unknown period