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Pain reduction was measured using the Visual Analog Scale (VAS) at baseline, three weeks, and three months

However, conflicting data exist regarding Treg frequency and function in peripheral blood mononuclear cells (PBMCs) of RA patients (143), with reports of increased (144, 145), normal (136, 137) or reduced (138, 139, 146, 147) numbers, potentially reflecting individual variations and disease activity status

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Supplementation studies in metabolically challenged populations have reported modest average effects on glucose and body weight markers

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