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Societal norms and behaviors may lead to differences in lifestyle, access to healthcare, and exposure to chronic stress, all of which impact the immune system over time [120]

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Enhanced Absorption: The nasal mucosa contains a rich network of blood vessels, which allows for rapid absorption of the active compounds

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Both GABA and serotonin availability declined with reduced receptor expression for GABA A 2 and GABAB1 in prefrontal cortex in the 2 week CMS (Tyagi et al., 2025)