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showed that (93), tetrandrine can down-regulate the expression or activation of Akt/JNK, MMP-2, MMP-9, and fibrous F-actin and focal adhesion kinase FAK, reduce the expression of migration-related proteins Rac1, Cdc42 and RhoA in MH7A cells, and block the migration and invasion of RA-FLS
Fitsanakis VA, Aschner M (2005) The importance of glutamate, glycine, and -aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity
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