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Cardiovascular Diabetol
J., Kopec, J., Hyung, S
PRDX1 stabilizes NFE2L2 by inhibiting cullin 3 (CUL3)-mediated ubiquitination, thereby promoting transcription of genes involved in GSH synthesis ( GCLC , GCLM ) and cystine import ( SLC7A11 ) 113
Therefore, blocking BRAF kinase function with BRAF inhibitors reduces glycolysis and induces oxidative phosphorylation, which is promising in preventing melanoma progression
In recent years, with the rapid pace of peoples lives, long-term irregular diet, coupled with a large amount of smoking and alcoholism, not only increase the burden of the gastrointestinal tract but also bring serious damage to the gastric mucosa
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