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Last page review: 2026-05-31

However, even after correcting serum vitamin B 12 and its metabolite levels, or haematological abnormalities, the ability to reverse cognitive impairment (dementia) and neurological disorders is not promising.50 51 52 The longer the time the neurological disorder or cognitive impairment presents before treatment, the less likely it can be reversed

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at high doses , it can become neurotoxic or act as a pro-oxidant

Esto plantea la pregunta de si la disfuncin mitocondrial podra ser un factor que cause la progresin de la enfermedad