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After 2 weeks of treatment, mice treated with GLP-1MK-801, as well as those subjected to calorie restriction or GLP-1 monotherapy, demonstrated enhanced glucose tolerance compared with mice that were treated with the vehicle or MK-801 monotherapy (Extended Data Fig

Both medications offer meaningful benefits for weight management and blood sugar control, but the choice between them can also depend on factors such as your personal response, side effect tolerance and convenience preferences

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