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food 18, 818823

doi: 10.3390/foods14050745 231 KimMJYangYJMinGYHeoJWSonJDYouYZet al

3.2.3 Sex hormones abnormalities Many research has discovered sex differences in the prevalence of both GD and depression, with a reported male-to-female ratio of 1:4-6 in GD and a ratio of roughly 1:2 in major depressive disorder (122, 128, 129)

Table 1 Global Response Assessment Scale Number Response Grading (%) Outcome 1 Significantly worse 0 Failure of the therapy 2 Somewhat worse 1 to 25 Failure of the therapy 3 Unchanged (neither worse nor better) 26 to 50 Failure of the therapy 4 Somewhat improved 51 to 75 Successful therapy 5 Significantly improved 76 to 100 Successful therapy Inclusion criteria This study included patients with moderate to severe interstitial cystitis who had participated in the experimental trial conducted in January 2023 at the UroGyn Specialists of Florida clinic using the nonFDA-approved BPC-157 peptide