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One review of the field stated that intranasal drug delivery has emerged as a reliable method to bypass the BBB and treat neurological diseases. Its not a done deal, though

Consistent gross recording, venography, ECG, pressure, microscopy and biochemistry assessment clearly described the aggressive syndrome of the occluded superior sagittal sinus

CRC, Boca Raton, p 370 Krahn MM, Ylitalo GM, Buzitis J, Chan SL, Varanasi U (1993) Rapid high-performance liquid-chromatographic methods that screen aromatic compounds in environmental samples

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