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While non-randomized trials can come with certain biases, the study has enough participants to show a statistically significant difference, said Lexchin, adding its scope is narrow because it considers only gastrointestinal harms rather than effects on other organs, such as the heart

The weight loss is not fast enough Great

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Wegovy is FDA-approved for weight management in people with a BMI (body mass index) of 30 or higher or 27 or higher if they have at least one weight-related medical condition, such as: High blood pressure ( hypertension ) Type 2 diabetes High cholesterol Sleep apnea Ozempic is FDA-approved for type 2 diabetes, but since it also contains semaglutide, its often prescribed off-label to help support weight management