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Glycemic control was encouraged with diet and exercise per discretion of site/physician

a direct causal link in humans has not been established, but patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should avoid this class of medicine [16] [17] Gallbladder disease rapid weight loss can increase the risk of gallstones and gallbladder inflammation [25] [26] Diabetic retinopathy rapid improvement in glycaemic control has been associated with worsening of diabetic retinopathy in people with pre-existing disease