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One of the most common causes of dry eye syndrome (keratoconjunctivitis sicca) is decreased tear production resulting from age, medical conditions (diabetes, rheumatoid arthritis, thyroid disorders), and certain medications

Improve blood sugar control by increasing insulin secretion

At 24 weeks, the mean weight reduction was 17.5% (41.2 lb)

49 Mechanistically, the effects of SCFAs on T cells do not rely on GPR41 or GPR43 but rather on the direct inhibitory activity of HDACs

Given the increasing interest in the GLP-1 target, we downloaded clinical trial data for ~3,800 GLP-1 related studies through July 2024 and asked, what other conditions are GLP-1 modulating drugs being tested for