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Description

2023;13(10):e071766

Front Endocrinol (Lausanne), 2013

Rated for 60A+

Epimerization of CDCA yields ursodeoxycholic acid (UDCA), an important bile acid metabolite involved in regulating the composition of gut microbiota as well as being important for fat soluble vitamin absorption

Reactive Fe 2+ in the labile iron pool is involved in the Fenton reaction, leading to the production of ROS, particularly hydroxyl radicals that contribute to oxidative damage of membrane lipids and ferroptosis [37]