glp 1 and gip mechanism of action Beyond the pancreas: contrasting cardiometabolic actions GLP1 Biology of Incretins: GLP-1 and

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In contrast to the short-access model, rats in the extended-access protocol may exhibit reduced sensitivity to LIRs modulation of dopamine-driven reinforcement, suggesting that more intensive or selective interventions would be needed to produce a behavioral effect

The peptide also enhances the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), critical molecules for neuronal survival and plasticity

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As the disease progresses, cortical atrophy and white matter loss become more pronounced